Creams & Ointments

Pharmaceutical cream or ointment is used as a means of delivering an active ingredient directly to the required area of the skin. Products can be either a water-in-oil (w/o) or oil-in-water (o/w) emulsion, consisting of waxes, emollients and lubricants dispersed in an oil phase, and a water phase containing emulsifying, stabilizing and thickening agents, preservatives and in some cases, colorant. Active ingredients are dispersed in either phase or added when the emulsion has been formed and allowed to cool.

Manufacture of pharmaceutical creams and ointments presents a number of challenges; A Silverson mixer can rapidly disperse solids into liquids, hydrate thickening and stabilizing agents, break down agglomerates and finely reduce particle and globule size to form stable emulsions and suspensions. Mixing times are dramatically reduced, while product uniformity and consistency are greatly improved. To learn more about this application, please read the report below.

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